What does the term "drug dependence" refer to?

The term "drug dependence" specifically refers to a physical or psychological state of reliance on a dangerous drug. This encompasses the idea that an individual may develop a compulsion to seek out the drug, often using it to the point where it leads to detrimental effects on their health and daily functioning. Dependence can manifest as tolerance, where increasing amounts of the drug are needed to achieve the same effect, and withdrawal symptoms occur when the drug is not consumed.

The nature of drug dependence indicates a significant alteration in the brain's chemistry and function, particularly with substances categorized as dangerous or addictive. This is different from merely social reliance or casual use, as drug dependence implies a consistent struggle with the management of substance use, often regardless of negative consequences. The psychological aspect may involve cravings, while the physical aspect might include withdrawal symptoms which underline the complicated and serious nature of drug dependence.