Extreme withdrawal symptoms from heroin can include which of the following?

Extreme withdrawal symptoms from heroin can include cramps, runny eyes, and a runny nose. When someone who is dependent on heroin stops using it, they often experience a range of physical and psychological symptoms as their body reacts to the absence of the drug. Cramps can result from the body's attempt to adjust to the lack of opioids, leading to intense discomfort. Runny eyes and nose are common physical manifestations of withdrawal, akin to symptoms one might experience with a cold, demonstrating how the body becomes reliant on the drug to function normally. These symptoms signify the body's physiological response to the deprivation of heroin, highlighting the severity of withdrawal in individuals with addiction.